| Cage, Nicolas |
Frank Pierce |
| Arquette, Patricia |
Mary Burke |
| Goodman, John |
Larry Verber |
| Rhames, Ving |
Marcus |
| Sizemore, Tom |
Tom Wall |
| Anthony, Marc |
Noel |
| Hurt, Mary Beth |
Nurse Constance |
| Curtis, Cliff |
Cy Coates |
| Serrano, Nestor |
Dr. Hazmat |
| Turturro, Aida |
Nurse Crupp |
| Sohn, Sonja |
Kanita |
| Roman, Cynthia |
Rose |
| Omilami, Afemo |
Griss |
| Johnson, Cullen O. |
Mr. Burke (as Cullen Oliver Johnson) |
| Nascarella, Arthur J. |
Captain Barney |
| Scorsese, Martin |
Dispatcher (voice) |
| Soelistyo, Julyana |
Sister Fetus |
| Lecube, Graciela |
Neighbor Woman |
| Burke, Marylouise |
Neighbor Woman |
| Somerville, Phyllis |
Mrs. Burke |
| Diveny, Mary |
Neighbor Woman |
| Farrell, Tom Riis |
John Burke |
| Shaklin, Aleks |
Arguing Russian |
| Citer, Leonid |
Arguing Russian |
| Rosario, Jr., Jesus A. Del |
Man with Bloody Foot |
| Fessenden, Larry |
Cokehead |
| Friedman, Bernie |
Big Feet |
| Kogan, Theo |
Prostitute |
| Walker, Fuschia |
Prostitute |
| Heffernan, John |
Mr. Oh |
| Maher, Matthew |
Mr. Oh's Friend |
| Dudley, Bronson |
Mr. Oh's Friend |
| McDonald, Marilyn |
Mr. Oh's Friend |
| Jupp, Jr., Ed |
Homeless Man in Waiting Room |
| Hoffman, J. Stanford |
Homeless Man in Waiting Room |
| Schrager, Rita Norona |
Concerned Hispanic Aunt |
| Berry, Don |
Naked Man |
| Gant, Mtume |
Street Punk |
| Noto, Michael A. |
Grunt |
| Scroggins, Omar |
Bystander (as Omar Sharif Scroggins) |
| Schemer, MuMs Da |
Voice in Crowd (as muMs) |
| Williams, Michael K. |
Drug Dealer (as Michael Kenneth Williams) |
| Davoli, Andrew |
Stanley |
| Hunter, Charlene |
Miss Williams |
| Malin, Jesse |
Club Doorman |
| Simon, Harper |
I.B. Bangin' aka Frederick Smith |
| Abrahams, Jon |
Club Bystander |
| Michaelson, Charis |
I.B.'s Girlfriend |
| Yang, Lia |
Dr. Milagros |
| Pagan, Antone |
Arrested Man |
| Marsala, Melissa |
Bridge & Tunnel Girl |
| Miller, Betty |
Weeping Woman |
| Gomez, Rosemary |
Pregnant Maria |
| Rodriguez, Luis |
Carlos |
| Kelegian, Sylva |
Crackhead |
| Ciornei, Frank |
Dr. Mishra |
| Ganey, Catrina |
Nurse Odette |
| Newman, Jennifer Lane |
Nurse Advisor |
| Bal, John |
Policeman in Hospital |
| Cassar, Raymond |
Policeman in Hospital |
| Cappadona, Tom |
Drunk |
| O'Connell, Jack |
Drunk |
| Foster, Randy |
Drunk |
| Spore, Richard |
Homeless Suicidal |
| Hanlon, James |
Fireman |
| Edwards, Chris |
Fireman |
| Giordano, Mark |
Police Sergeant |
| Mulheren, Michael |
Cop in Elevator |
| Zayas, David |
Cop in Elevator |
| Serpico, Terry |
Cop #1 |
| Smyj, Brian |
Cop #2 |
| Resnick, Floyd |
Cop #3 |
| Leigh, Megan |
Surgeon |
| Vasquez, David |
Screaming Man |
| Reyes, Judy |
ICU Nurse |
| Reidy, Joseph P. |
ICU Nurse (as Joseph Reidy) |
| Latifah, Queen |
Dispatcher Love (voice) |
| Campbell, Carolyn |
Policewoman (uncredited) |
| Connelly, Joe |
Catatonic Patient in brown suede coat (uncredited) |
| DeFinna, Bart |
Restaurant Cashier (uncredited) |
| Miller, George F. |
Paramedic in the hallway at the hospital (uncredited) |
| Webb, Joseph Monroe |
Drummer (uncredited) |
